Do you sleep less than five hours? Genetic study indicates this could increase the risk of developing depression

Consistently sleeping less than five hours each night could increase the risk of developing depressive symptomsaccording to a genetic study led by researchers at the University College London (UCL).

The results are published in the journal Translational Psychiatry and the study analyzed data from people with an average age of 65 years: Little sleep is associated with the appearance of depressive symptoms.

Historically, poor sleep has been considered a bad side effect mental healthbut this research found that the link between sleep and mental illness is more complex, says a statement from UCL.

“We have this chicken-or-egg scenario between suboptimal sleep duration and depression (…). Using genetic susceptibility to the disease, we determined that sleep is likely to precede depressive symptoms, rather than the other way around,” says Odessa S. Hamilton, author of the work.

Researchers used genetic and health data from 7,146 people recruited into the ELSA Longitudinal Aging Study, a nationally representative population-based report in England.

The team assessed the strength of genetic predisposition among participants, using results from previous genome-wide association studies that have identified thousands of genetic variants linked to a higher likelihood of developing depression and short or long sleep.

They found that people with a greater genetic predisposition to short sleep (less than five hours in a night) were more likely to develop depressive symptoms within 4-12 years.

However, people with a greater genetic predisposition to depression were not more likely to Sleep a little.

In the words of Olesya Ajnakina, also from UCL, “the short and long sleep durationalong with depression, are factors that contribute greatly to the public health burden and are highly heritable.”

“Polygenic scores, indices of an individual’s genetic propensity for a trait, are considered key to beginning to understand the nature of sleep duration and depressive symptoms.”

For Andrew Steptoe, “suboptimal sleep and depression increase with age, and with the global phenomenon of population aging there is a growing need to better understand the mechanism that connects depression.”

“This study lays an important foundation for future research into the intersection of genetics, sleep, and depressive symptoms.”

On the other hand, and in another non-genetic analysis, the researchers also revealed a link between sleeping a lot and developing depressive symptoms: participants who slept more than nine hours were 1.5 times more likely to develop depressive symptoms than those who slept an average of seven hours,